Products Description
Need a high-purity filter element for sterile or high-purity fluid applications? Guanjiang's Sanitary Filter Element is a precision filtration component specifically designed for applications requiring strict hygiene standards — pharmaceuticals, food and beverage, and biotechnology. Manufactured using FDA-compliant materials and sanitary design principles, it ensures contaminant removal while maintaining product purity and process integrity. Featuring a pleated configuration with specialized filter media (PES, PVDF, or Nylon), the coreless design and smooth surface finish facilitate optimal flow and thorough cleaning — supporting CIP (Clean-in-Place) and SIP (Sterilize-in-Place) processes.
Key Advantages
Hygienic Design
Smooth surface finish (Ra ≤ 0.8 μm) prevents bacterial adhesion and biofilm formation. Coreless construction eliminates internal cavities. Fully drainable for complete fluid removal.
99.99% Efficiency @ 0.1μm
High filtration efficiency for particles ≥0.1μm. Low protein binding for biopharmaceutical applications. Consistent pore size ensures reliable particle retention.
Broad Chemical Compatibility
Resistant to acids, bases, and solvents. Withstands aggressive cleaning agents and high-temperature sterilization. Maintains integrity after repeated CIP/SIP cycles.
FDA, USP & cGMP Compliant
Meets FDA 21 CFR 177, USP Class VI, cGMP, EHEDG, and 3-A Sanitary Standards. Full material traceability available.
High Dirt-Holding Capacity
Extended service life — lower replacement frequency. High dirt-holding capacity reduces operating costs.
Low Pressure Drop
Optimized pleat geometry reduces energy consumption — maintains high flow rates with minimal resistance.
Easy Installation
Standard cartridge design — quick and easy replacement. Minimizes downtime during filter changeovers.
Filter Media Selection Guide
PES (Polyethersulfone)
Low protein binding, high flow rates, broad pH range (1-14). Ideal for biopharmaceutical and tissue culture media sterilization.
PVDF (Polyvinylidene Fluoride)
Excellent chemical resistance, hydrophobic, low extractables. Ideal for aggressive chemicals, solvents, and gas filtration.
Nylon (Polyamide)
Good chemical resistance, high flow rates, naturally hydrophilic. Ideal for aqueous solutions to moderate solvents.
PTFE (Polytetrafluoroethylene)
Maximum chemical resistance, hydrophobic, high-temperature stability. Ideal for aggressive chemicals, gases, and venting.
Technical Specifications
| Parameter | Specification |
|---|---|
| Filter Media Options | PES / PVDF / Nylon / PTFE |
| Filtration Precision | 0.1μm / 0.22μm / 0.45μm / 1.0μm / 5.0μm / 10.0μm |
| Filtration Efficiency | ≥ 99.99% @ 0.1μm (for rated precision) |
| Length Options | 5" / 10" / 20" / 30" / 40" / Custom |
| Outer Diameter | 2.7" (68mm) / 2.8" (70mm) / Custom |
| End Cap Types | 226 / 222 / 215 / Flat / DOE (Double Open End) |
| Cage Material | Polypropylene / Stainless steel (sanitary) |
| Operating Temperature | Up to 85°C (PES) / 65°C (Nylon) / 130°C (PTFE) |
| Bubble Point (0.22μm) | ≥ 340 kPa (PES) / ≥ 280 kPa (PVDF) / ≥ 310 kPa (Nylon) |
Sterilization & Validation:
Sterilization methods: Autoclaving (up to 135°C, 30 min) / In-line steam (SIP) / Gamma irradiation (up to 50 kGy)
Integrity testing: Bubble point / Diffusion test / Water intrusion (hydrophobic membranes)
Validation support: Extractables testing / Bacterial retention validation / Compatibility studies — documentation available upon request.
Applications
| Industry | Typical Applications |
|---|---|
| Pharmaceutical | Purified water (PW/WFI), buffer solution sterilization, fermentation air filtration, API intermediate |
| Food & Beverage | Product final filtration, CIP return filtration, ingredient purification, beverage polishing |
| Biotechnology | Cell culture media filtration, harvest fluid clarification, buffer sterilization, viral clearance |
| Cosmetics | Raw material filtration, product polishing, water purification, preservative removal |
Frequently Asked Questions
Q1: How do I select the right filter media for my application?
A: PES — best for biopharmaceutical (low protein binding, high flow). PVDF — aggressive chemicals, solvents, gas. Nylon — general aqueous solutions. PTFE — maximum chemical resistance, hydrophobic. See our selection guide above. Contact us with your fluid composition for a recommendation.
Q2: What is the purpose of the coreless design?
A: Traditional filter elements have a rigid plastic core that can create dead legs and hard-to-clean areas. Our coreless design eliminates these internal cavities — preventing contaminant accumulation, improving drainability, and facilitating more thorough cleaning. This is essential for GMP-compliant pharmaceutical and food applications.
Q3: Can the filter element be used for sterile filtration?
A: Yes. Our 0.22μm and 0.1μm rated elements are validated for sterile filtration according to ASTM F838-20 standards (Brevundimonas diminuta retention). They are suitable for sterilizing-grade applications in pharmaceutical, biotech, and food processing. Validation documentation is available upon request.
Q4: How do you perform integrity testing on sanitary filter elements?
A: Common integrity test methods include: Bubble point (for aqueous and solvent systems), Diffusion test (Forward Flow), and Water intrusion test (for hydrophobic membranes). We provide recommended integrity test values with each element. Automated filter integrity testers can be used.
Q5: What documentation is provided for pharmaceutical validation?
A: We provide comprehensive validation documentation: material certificates (FDA/USP Class VI), extractables reports, bubble point certificates, bacterial retention validation, and batch-specific quality records. Full traceability from raw material to finished element. Contact us for a validation guide specific to your application.
Need a sanitary filter element for your high-purity fluid application?
Request a Quote → Download Datasheet (PDF)* Please provide your filtration precision (μm), length, end cap type, filter media (PES/PVDF/Nylon/PTFE), and any sterilization requirements for a fast, accurate quotation.
